Google

蓝海人类学在线 Ryan WEI's Forum of Anthropology

 找回密码
 注册
查看: 3116|回复: 1

高密度SNP显示德系犹太人与非犹太裔的欧裔美国人区别明显

[复制链接]
发表于 2009-11-1 23:02 | 显示全部楼层 |阅读模式
Genome Biology doi:10.1186/gb-2009-10-1-r7

A genome-wide genetic signature of Jewish ancestry perfectly separates individuals with and without full Jewish ancestry in a large random sample of European Americans
Anna C Need et al.
Abstract
Background
It was recently shown that the genetic distinction between self-identified Ashkenazi Jewish and non-Jewish individuals is a prominent component of genome-wide patterns of genetic variation in European Americans. No study however has yet assessed how accurately self-identified (Ashkenazi) Jewish ancestry can be inferred from genomic information, nor whether the degree of Jewish ancestry can be inferred among individuals with fewer than four Jewish grandparents.
Results
Using a principal components analysis, we found that the individuals with full Jewish ancestry formed a clearly distinct cluster from those individuals with no Jewish ancestry. Using the position on the first principal component axis, every single individual with self-reported full Jewish ancestry had a higher score than any individual with no Jewish ancestry.
Conclusions
Here we show that within Americans of European ancestry there is a perfect genetic corollary of Jewish ancestry which, in principle, would permit near perfect genetic inference of Ashkenazi Jewish ancestry. In fact, even subjects with a single Jewish grandparent can be statistically distinguished from those without Jewish ancestry. We also found that subjects with Jewish ancestry were slightly more heterozygous than the subjects with no Jewish ancestry, suggesting that the genetic distinction between Jews and non-Jews may be more attributable to a Near-Eastern origin for Jewish populations than to population bottlenecks.

发表,阅读
A genome-wide genetic signature of Jewish ancestry.jpg
 楼主| 发表于 2009-11-1 23:03 | 显示全部楼层
以色列海法大学Behar写的一个ppt,可以看看。 一段时间以色列人以母系计算血统,因此文中主要讨论母系。

Our ForeMothers- Researching the Common Ancestry of Ashkenazi
您需要登录后才可以回帖 登录 | 注册

本版积分规则

小黑屋|手机版|Archiver|人类生物学在线 ( 苏ICP备16053048号 )

GMT+8, 2020-2-24 00:41 , Processed in 0.084876 second(s), 19 queries .

Powered by Discuz! X3.4

© 2001-2017 Comsenz Inc.

快速回复 返回顶部 返回列表