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蓝海人类学在线 Ryan WEI's Forum of Anthropology

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The fine-scale genetic structure of the British population

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发表于 2015-3-19 17:53 | 显示全部楼层 |阅读模式
Fine-scale genetic variation between human populations is interesting as a signature of historical demographic events and because of its potential for confounding disease studies. We use haplotype-based statistical methods to analyse genome-wide single nucleotide polymorphism (SNP) data from a carefully chosen geographically diverse sample of 2,039 individuals from the United Kingdom. This reveals a rich and detailed pattern of genetic differentiation with remarkable concordance between genetic clusters and geography. The regional genetic differentiation and differing patterns of shared ancestry with 6,209 individuals from across Europe carry clear signals of historical demographic events. We estimate the genetic contribution to southeastern England from Anglo-Saxon migrations to be under half, and identify the regions not carrying genetic material from these migrations. We suggest significant pre-Roman but post-Mesolithic movement into southeastern England from continental Europe, and show that in non-Saxon parts of the United Kingdom, there exist genetically differentiated subgroups rather than a general ‘Celtic’ population.

[size=14.4949998855591px]http://www.nature.com/nature/journal/v519/n7543/full/nature14230.html
发表于 2015-3-19 18:08 | 显示全部楼层
数据公开了吗?谁找找贴一下连接。
 楼主| 发表于 2015-3-19 18:17 | 显示全部楼层
有链接啊,正式见刊的,页码都有了。
发表于 2015-3-19 18:25 | 显示全部楼层
牛X,抽时间研究下。谢。
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