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总结:犹太人牧师的Y-SNP支系,主要论及科恩家族

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发表于 2009-8-30 11:41 | 显示全部楼层 |阅读模式
本帖最后由 ranhaer 于 2009-8-30 12:56 编辑

Human Genetics doi:10.1007/s00439-009-0727-5

Extended Y chromosome haplotypes resolve multiple and unique lineages of the Jewish priesthood
Michael F. Hammer et al.
Abstract
It has been known for over a decade that a majority of men who self report as members of the Jewish priesthood (Cohanim) carry a characteristic Y chromosome haplotype termed the Cohen Modal Haplotype (CMH). The CMH has since been used to trace putative Jewish ancestral origins of various populations. However, the limited number of binary and STR Y chromosome markers used previously did not provide the phylogenetic resolution needed to infer the number of independent paternal lineages that are encompassed within the Cohanim or their coalescence times. Accordingly, we have genotyped 75 binary markers and 12 Y-STRs in a sample of 215 Cohanim from diverse Jewish communities, 1,575 Jewish men from across the range of the Jewish Diaspora, and 2,099 non-Jewish men from the Near East, Europe, Central Asia, and India. While Cohanim from diverse backgrounds carry a total of 21 Y chromosome haplogroups, 5 haplogroups account for 79.5% of Cohanim Y chromosomes. The most frequent Cohanim lineage (46.1%) is marked by the recently reported P58 T->C mutation, which is prevalent in the Near East. Based on genotypes at 12 Y-STRs, we identify an extended CMH on the J-P58* background that predominates in both Ashkenazi and non-Ashkenazi Cohanim and is remarkably absent in non-Jews. The estimated divergence time of this lineage based on 17 STRs is 3,190 ± 1,090 years. Notably, the second most frequent Cohanim lineage (J-M410*, 14.4%) contains an extended modal haplotype that is also limited to Ashkenazi and non-Ashkenazi Cohanim and is estimated to be 4.2 ± 1.3 ky old. These results support the hypothesis of a common origin of the CMH in the Near East well before the dispersion of the Jewish people into separate communities, and indicate that the majority of contemporary Jewish priests descend from a limited number of paternal lineages.

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 楼主| 发表于 2009-8-30 11:43 | 显示全部楼层
论文的结果支持 科恩家族单倍型CMH 有共同的中东起源,并且大多数犹太牧师起源与数目有限的男性祖先。
发表于 2014-1-26 13:32 | 显示全部楼层
原文與附件免費下載 http://link.springer.com/article/10.1007%2Fs00439-009-0727-5

A comment on the paper Hammer 2009a.pdf (310.42 KB, 下载次数: 40)
发表于 2014-1-26 18:31 | 显示全部楼层
你好Anthro,请问你有没有这篇文章,(Y-chromosome Haplogroup O3-M122 Variation in East Asia and Its Implications for the Peopling of Korea)。
发表于 2014-1-26 19:56 | 显示全部楼层
6# 奋斗 I can not upload to the file. because it is size too large. Tell me your email address, please.
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