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y染色体DNA支持狗起源于长江以南的亚洲

本帖最后由 198401 于 2011-11-24 09:56 编辑

Origins of domestic dog in Southern East Asia is supported by analysis of Y-chromosome DNA

Z-L Ding et al.

Global mitochondrial DNA (mtDNA) data indicates that the dog originates from domestication of wolf in Asia South of Yangtze River (ASY), with minor genetic contributions from dog–wolf hybridisation elsewhere. Archaeological data and autosomal single nucleotide polymorphism data have instead suggested that dogs originate from Europe and/or South West Asia but, because these datasets lack data from ASY, evidence pointing to ASY may have been overlooked. Analyses of additional markers for global datasets, including ASY, are therefore necessary to test if mtDNA phylogeography reflects the actual dog history and not merely stochastic events or selection. Here, we analyse 14 437 bp of Y-chromosome DNA sequence in 151 dogs sampled worldwide. We found 28 haplotypes distributed in five haplogroups. Two haplogroups were universally shared and included three haplotypes carried by 46% of all dogs, but two other haplogroups were primarily restricted to East Asia. Highest genetic diversity and virtually complete phylogenetic coverage was found within ASY. The 151 dogs were estimated to originate from 13–24 wolf founders, but there was no indication of post-domestication dog–wolf hybridisations. Thus, Y-chromosome and mtDNA data give strikingly similar pictures of dog phylogeography, most importantly that roughly 50% of the gene pools are shared universally but only ASY has nearly the full range of genetic diversity, such that the gene pools in all other regions may derive from ASY. This corroborates that ASY was the principal, and possibly sole region of wolf domestication, that a large number of wolves were domesticated, and that subsequent dog–wolf hybridisation contributed modestly to the dog gene pool.

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hdy2011114f1.jpg
2011-11-24 09:56
与以前的一篇《狗起源于中东灰狼》不同。
http://www.ranhaer.com/viewthrea ... 0%B6%AB%BB%D2%C0%C7
对于狗、猪这样广泛分布、容易驯化的动物,应当考虑几个中心独立驯化的可能性。
另外,研究猪狗的驯化,不能不参照野生的狼和野猪的分布。猪狗驯化过程中,与野生种群杂交的事时有发生。这个也不能不考虑。
O3a3c* (M134+, M117-)
结论很成问题,各地的主要单倍体群分布差异性非常强,欧洲北非高频的HG1虽然也存在于东方,但来自东亚,并不合乎逻辑。
还是老话题,多态性高可能是分化中心,也可能是迁徙混合叠加所致。
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与以前的一篇《狗起源于中东灰狼》不同。
http://www.ranhaer.com/viewthread.php?tid=14810&highlight=%D6%D0%B6%AB%BB%D2%C0%C7
198401 发表于 2011-11-24 10:02
注意这篇文献,也是通过与野狼的对比,否定了之前基于东亚家狗mtdna多态性更高所以更似起源地的推测,这篇y-dna文献也有着同样的问题,未对比野狼的谱系,因此结论很成问题。
新技术方案尝试:低覆盖全基因组,最低成本深度解析父系源流,略有成效,大家一起摸索。微博@基因人王冰 QQ群:387100816。
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