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Artificial selection on brain expressed genes during the domestication of dog

Artificial selection on brain expressed genes during the domestication of dog

Yan Li etc.

Abstract

Domesticated dogs have many unique behaviors not found in gray wolves that have augmented their interaction and communication with humans. The genetic basis of such unique behaviors in dogs remains poorly understood. We found that genes within regions highly differentiated between outbred Chinese native dogs and wolves show high bias for expression localized to brain tissues, particularly the prefrontal cortex, a specific region responsible for complex cognitive behaviors. In contrast, candidate genes showing high population differentiation between Chinese native dogs and German Shepherd dogs did not demonstrate significant expression bias. These observations indicate that these candidate genes highly expressed in the brain have rapidly evolved. This rapid evolution was probably driven by artificial selection during the primary transition from wolves to ancient dogs, and was consistent with the evolution of dog-specific characteristics, such as behavior transformation, for thousands of years.

http://mbe.oxfordjournals.org/content/early/2013/05/08/molbev.mst088.short
这。。。。。和人一样么。。。照抄人的结论还是???? 这成神了
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